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University of Birmingham

College of Medical and Dental Sciences

School of Clinical and Experimental Medicine

Applications are invited from outstanding individuals with ambition to develop their independent research to work for 3.5 years under the supervision of Professor Ferenc Mueller, Professor of Developmental Genetics, on a Wellcome Trust Investigator grant. This programme is carried out in close collaboration with the computational biologist Professor Boris Lenhard at Imperial College London. The Mueller laboratory studies gene regulation in vertebrate development using interdisciplinary approaches. For recent publications and field of research see: www.birmingham.ac.uk/Ferenc-Mueller. Their research is integrated in the Birmingham Centre for Genome Biology www.birmingham.ac.uk/genome-biology.

The fellow will study how developmental regulation of genes is mediated by long-range cis-regulatory interactions. The successful candidate will combine genome wide sequencing based tools of enhancer and promoter activity profiling and apply programmable genome editing together with the power of zebrafish transgenesis to elucidate the functional consequences of predicted cis-regulatory interactions in development. The project will take advantage of the benefits of the zebrafish for imaging by high resolution in vivo microscopy.

The successful applicants will have a first degree and a PhD in an area of specialism relevant to the project. They will also have strong background in molecular biology, experience with genomics data interpretation, and/or genetic manipulation in a vertebrate model organism.

The posts are available from April for a period of 3 years (likely extendable by 6 months). Informal enquiries should be directed to Prof. Ferenc Mueller tel: +44 (0)12142895; email f.mueller@bham.ac.uk

Full time starting salary is normally in the range £29,301 to £38,183. With potential progression once in post to £40,523 a year.

 

Closing date: 9th March; Ref: 54650 

Details from 0121 415 9000 or www.hr.bham.ac.uk/jobs HR, University of Birmingham, Edgbaston, Birmingham B15 2TT

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