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Postdoctoral Fellow Position in Zebrafish Drug Discovery / Neuroscience -  St. Michael’s Hospital

Position: Postdoctoral Fellow

Location: Keenan Research Centre for Biomedical Science

Department: Medicine

Reports to: Principal Investigator

Hours: 37.5 hours / week

Status: Full-time, two-year contract

Salary: $40,000 - $50,000 + benefits + vacations + health insurance

Description:

A postdoctoral position is available in the Brain & Breathing Science Lab at the Keenan Research Centre for Biomedical Science at St. Michael’s Hospital (www.gasplab.com).

Our lab focuses on understanding the neural mechanisms underlying opioid-induced respiratory depression using rodent models and at finding novel therapies to prevent opioid overdoses using zebrafish. The Brain & Breathing Lab is collaborating with the Zebrafish Centre for Advanced Drug Discovery.

We are currently looking for a postdoctoral fellow to help establish a new, phenotype-based high-throughput platform in zebrafish to identify target genes and new drug compounds that could prevent respiratory depression with opioid overdose, while preserving the analgesic properties of opioids.

Key Responsibilities:

- Implement, test, and enhance our existing platform in zebrafish.

- Test chemical libraries such as FDA-approved and repurposing drug libraries.  

- Develop gene screening approaches in zebrafish to identify key-genes involved in the regulation of breathing in zebrafish

Qualifications:

- A recently obtained PhD in Drug and/or Gene Discovery in Zebrafish and Neuroscience.

- Experience and expertise with zebrafish, genes knockdown with morpholino oligonucleotides, and drug screening

- Relevant first-author publications.

- Excellent skills in scientific writing and verbal presentation in English with a recent publication track record

- Expertise in Neuroscience is preferred but not mandatory.

- Please do not apply if your PhD is not related to zebrafish or drug screening.

Application:

Submit/attach a complete application as a single PDF file including 1) curriculum vitae, 2) one-page statement describing applicant’s accomplishments, 3) copies of relevant in-press, submitted articles, 4) names and email addresses of 3 referees.

Submit application to gasp.lab@gmail.com

Thank you for your application, only those selected for an interview will be contacted.

Closing date. June 30, 2018.

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