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Postdoc Position in Biology/Biotechnology Available – Department of Pediatrics I - University Children’s Hospital Heidelberg

(Full-time, 100%)

 

The University Children’s Hospital invites applications for the position of a Postdoc within the Department of Pediatrics I.

The position is full-time (100%) and limited to 30 months with the option of extension. Salary is according to TV-L.

 

The project is embedded in a cooperation project between the University Children’s Hospital Heidelberg and BioQuant and the private companies ACQUIFER/DITABIS and Rapp OptoElectronic GmbH, which is funded by the Federal Ministry for Economic Affairs and Energy. Ultimate goal of this project is the development of a novel in vivo high-content screening platform that permits automated laser-assisted photomanipulation and photoablation of target structures in the larval zebrafish. This photoablation pipeline will be used to develop a model for acute kidney injury in zebrafish and, subsequently, to perform a high content screen for nephroprotective and regenerative substances.

You will work within a collaborative research team consisting of biologists, physicians, engineers and software developer.

 

To fulfil the position as Postdoc, applicants must have obtained a doctorate in biology or biotechnology. Previous experience working with zebrafish and high-content microscopy is preferred but not mandatory. Proficiency in the german language is not required.

 

Your duties and responsibilities

Development and validation of a laser-assisted and high-content compatible photoablation workflow for the induction of acute kidney injury in the larval zebrafish

Perform experimental work using zebrafish embryos and larvae (<5 dpf), e.g. microinjection, micromanipulation, compound treatment

Perform zebrafish husbandry tasks including handling of adults, crossings and embryo culture

Utilize automated high-content screening microscopes for chemical screening applications

Computer based analysis of large-scale image data by use of image processing tools

Immunohistochemistry of larval zebrafish, assays for cell death and proliferation, RNA in situ hybridization

Provide help and support in data analysis

Perform routine lab tasks and help with general laboratory management.

 

We offer to work within a highly motivated and interdisciplinary environment consisting of researchers of several scientific disciplines (biology, engineering, medicine). We expect a self-motivated and team oriented work attitude.

 

For applications and further details please contact

University of Heidelberg

Center for Pediatrics and Adolescent Medicine

Department of Pediatrics I

Dr. Jens H. Westhoff

Im Neuenheimer Feld 430

69120 Heidelberg, Germany

eMail: jens.westhoff@med.uni-heidelberg.de

 

This application closes November 30th 2017.

 

Please find the job announcement on our Career Site (in German): Postdoc (m/w) der Biologie/Biotechnologie

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