Skip to end of metadata
Go to start of metadata

This page represents a portion of the MGH/CVRC Zebrafish Server content, originally hosted at http://zebrafish.mgh.harvard.edu.


Zebrafish Map Data

We have constructed a zebrafish genetic linkage map consisting of 705 simple sequence-length polymorphism markers (SSLPs), using 44 F2 progeny from the AB x IN reference cross (see above). The map covers 2350 centimorgans (cM) of the zebrafish genome with an average resolution of 3.3 cM. It is a complete map in genetic mapping terms (there is one linkage group for each of the 25 chromosomes), and it has been confirmed by somatic-cell hybrids and centromere mapping using half-tetrad analysis. The markers are highly polymorphic in the zebrafish strains used for genetic crossees and provide a means to compare genetic segregation of developmental mutations between laboratories. These markers will provide an initial infrastructure for the positional cloning of the nearly 600 zebrafish genes identified as crucial to vertebrate development, and will become an important anchor for the physical map of the zebrafish genome.

Markers from the original reference cross release of data are included in the figures at the above link. For details on map construction, please refer to the manuscript cited above.


Map Data and Graphics