Blog from May, 2020

Full-Time Postdoctoral Fellow - Nechiporuk Lab
School of Medicine, Department of Cell, Developmental & Cancer Biology
Portland, Oregon

Job Summary
This full-time (1.0FTE) position for a junior level PhD post-doctoral researcher will provide a mechanism for the hired individual to develop into a successful independent researcher in the fields of developmental biology. The Nechiporuk lab uses zebrafish as a model system to study the formation of the peripheral nervous system. The broad research focus is to discover mechanisms driving collective cell migration. The hired individual will use variety of modern approaches, including transgenesis, CRISPR-based genome editing, single-cell RNA sequencing (scRNA-seq), live imaging, and biochemical approaches, to dissect intracellular processes that drive collective cell migration during development. The proposed training will be conducted at Oregon Health & Science University in Portland, OR.

Salary and Benefits
The hiring salary for this position is set according to NIH guidelines.
Benefits include medical and dental insurance as well as retirement benefits.

Minimum Qualifications
PhD in life sciences such as genetics, anatomy, biology, biochemistry, or related field


Interested individuals should email their CV, short statement of research interests, and the names and contact information for three references to Alex Nechiporuk  (nechipor@ohsu.edu)

A postdoctoral fellow position is available immediately in the Lien Lab (Heart Regeneration Laboratory) at Children’s Hospital Los Angeles/University of Southern California. We are looking for a hard-working and passionate candidate interested in using zebrafish, and/or stem cell/organ culture to study molecular mechanisms of heart development, disease, and regeneration. The candidate will be involved in studying coronary and lymphatic vessel development and determine their roles in heart regeneration using various techniques including scRNAseq, generating and characterizing CRISPR mutants and molecular imaging.

A strong background in molecular biology, confocal imaging, and/or cell culture is required. Previous experience with generating transgenic and CRISPR mutant zebrafish is preferred but not required. Experience in (micro) surgery/dissection in mouse or zebrafish and in situ hybridization is also preferred but not required. A Ph.D. degree is required.
We offer competitive salary and excellent benefits. Interested candidates should submit their CV and names of 3 references to clien@chla.usc.edu.

The Blackburn laboratory at the University of Kentucky is recruiting a post-doctoral scholar. We are seeking outstanding and motivated individuals who will be part of an enthusiastic and goal-oriented team that studies mechanisms of cancer progression and relapse. The PI has a strong record of high impact publications, such as in Cancer Cell and Leukemia, and the laboratory has significant funding from the National Cancer Institute and the NIH Director’s Fund New Innovator Award. Projects will focus on analysis of leukemia stem cells and their niche, and the role of the tumor microenvironment in cancer progression. These projects will utilize cutting-edge in vivoimaging in zebrafish cancer models, single cell sequencing technologies, and biological and biochemical techniques (human cell culture, PCR, western blot, etc), with the goal of identifying new aspects of cancer biology that can ultimately be therapeutically targeted. Applicants should have a strong background in molecular biology and cell culture, and experience with zebrafish and/or microscopy is preferred. Successful applicants will be highly motivated with good communication skills, interest and experience in cancer research, a proven publication record, and the ability to work fairly independently. 

For further information about the Blackburn Lab visit our website www.blackburnlab-uky.com

The Blackburn Lab is part of the NCI-designated Markey Cancer Center. We are committed to the career development of our trainees and their success is our top priority. Postdoctoral scholars joining the lab would join a multi-disciplinary, highly collaborative training environment.

Salary will be at or above published guidelines of the National Institutes of Health, with travel funds available to attend national and international meetings. A multi-year commitment to post-doctoral training is expected.

Interested applicants should submit a curriculum vitae, a cover letter including short description of research interests, first-authored publications and name/contact information of 3 references to jsblackburn@uky.edu

The Centre for Developmental Neurobiology invites applications for tenure-track group leader positions in developmental neuroscience.

We are looking to recruit outstanding early career investigators who will make significant contributions to developmental neuroscience. We are particularly interested in proposals addressing human brain development and its genomic basis, the emergence of brain structure and function as well as neural plasticity and neurodevelopmental disorders. We are seeking innovative scientists with promising potential for developing an internationally recognised research programme. The originality of the candidate's work will take precedence over the sub-area of specialisation. Applicants should be seeking a stimulating interdisciplinary environment in which to pursue research.

Applications are welcomed from early career scientists who meet the eligibility criteria for career development fellowships (such as those offered by the Wellcome Trust and the Research Councils). Successful candidates will establish their own independent research group in the Centre supported by a fellowship and will then progress to a tenured post upon completion of their fellowship, subject to a satisfactory progress review. The Centre for Developmental Neurobiology has an excellent track record for tenure-track junior group leaders securing career development fellowships.  

Successful candidates will have their primary appointment at the Centre for Developmental Neurobiology within the Institute of Psychiatry, Psychology and Neuroscience at King’s College London. Depending on their research programme, candidates may also have a secondary appointment with the MRC Centre for Neurodevelopmental Disorders.

These posts are an exciting opportunity for early career academics to establish their own independent research group within King’s College London’s vibrant neuroscience research community. Successful candidates will be given office and laboratory space, access to state-of-the art core facilities, a PhD studentship and additional opportunities to recruit students from various PhD programmes. Mentorship from a senior faculty member and career development opportunities will also be provided.

To apply, please submit:

• A one-page summary of research achievements;

• A one-page outline of your proposed research;

• Your academic CV; and

• The names of three potential referees

to Dr Tamara al Janabi, Research Strategy Manager, via e-mail: tamara.al_janabi@kcl.ac.uk

Please write “Application for tenure-track group leader” in the subject of your e-mail.

For an informal discussion about the position, please contact Professor Oscar Marín via email:

oscar.marin@kcl.ac.uk. Please write “CDN tenure-track group leader” in the subject of your e-mail.

Closing date for receipt of applications is 23:59 GMT on 11^th June 2020.

The Centre for Developmental Neurobiology occupies the entire fourth floor of New Hunt's House, a multipurpose research and teaching building on the Guy's Campus of King's College London next to London Bridge in central London. The Centre has a team of over 150 researchers and is part of the Institute of Psychiatry, Psychology and Neuroscience, King’s College London. Our work focuses on understanding the mechanisms that control brain development and how deviations from the normal plan lead to disease. We carry out highly collaborative and multi-disciplinary studies using an array of model organisms (http://www.devneuro.org).

King’s College London values diversity and is committed to equality of opportunity. The Institute of Psychiatry, Psychology and Neuroscience has a dedicated Diversity and Inclusion team. You can read more about their work here: https://www.kcl.ac.uk/ioppn/diversity-inclusion/our-work/our-work.

Postdoctoral Position- Mechanisms of neurodegeneration in ALS and drug discovery

A postdoctoral research fellow opportunity is available in the Patten Lab at the Institut National de la

Recherche Scientifique (INRS) in the Greater Montreal area. His research group focuses on

investigating disease mechanisms and novel therapeutic approaches for neurological disorders

including amyotrophic lateral sclerosis (ALS). The laboratory uses a combination of zebrafish genetic

models, genome-editing approaches and chemical genetic screens. We are seeking for a candidate

to further our understanding of ALS pathogenesis and to development therapeutics for ALS. The

project will include application of confocal microscopy, cellular neurophysiology, drug screens,

genome editing and exciting molecular biology approaches. The post holder will benefit from brandnew

and state-of-the-art imaging and fish facilities of the Institute. Collaboration is critical for

progress - the Patten lab works closely with neuroscience labs at CRCHUM and McGill University

working with human IPSCs, mice and C. elegans.

The candidate will benefit from an intellectual environment, friendly and interactive culture of the neuroscience community in Montreal.

The candidate will have a PhD in biology, neuroscience or related field. Independence, motivation,

good communication skills and a willingness to work as part of a team are required. The candidate

will have the opportunity and be supported into developing new projects. The ideal candidate should

preferably have experience in imaging techniques, molecular biology and genome editing methods.

Candidates should submit curriculum vitae, a one-page summary of research interests and the

names and contact information for three references to Dr. Patten kessen.patten@iaf.inrs.ca

Professor Corinne Houart's lab is looking for a postdoctoral fellow to drive a drug screen to identify modifiers of FOXG1 pathology using a zebrafish genetic model. The screen will involve high resolution imaging of mutants in fluorescent double transgenic background and behavioural tests. 

The post is funded by FOXG1 Research Foundation. Experience in zebrafish research and imaging will be highly recommended. 

For more information please contact corinne.houart@kcl.ac.uk