We are looking for highly motivated individuals who share our passion for science and would like to work in a friendly and collaborative environment.
Fully funded PhD student positions are available in the laboratory of Dr. Peng Huang in the Department of Biochemistry and Molecular Biology
at the University of Calgary, Canada.
We use zebrafish as a model system to understand how tissue patterning is achieved and how tissue integrity is maintained. We study the spinal cord patterning to understand how different cell signaling pathways (Hedgehog and Notch signaling) interact during cell fate specification. We also study how non-muscle cells (e.g., tendon cells and muscle progenitor cells) contribute to muscle development, degeneration and regeneration. For more information about the lab and our recent publications, please visit: https://people.ucalgary.ca/~huangp/index.html
PhD student candidates should have a BS or MSc in Molecular Biology, Genetics, Developmental Biology or a related discipline, a strong academic background, good English skills and an enthusiasm for research. Previous lab experience with genetic model organisms is preferred but not required. Excellent written and verbal communication skills are critical.
To apply, please send a cover letter summarizing previous research experiences and future goals, the transcript and the CV with names of 2-3 references to Peng Huang, peng.huang@gmail.com with the subject line “PhD Student Position”. Application deadline: March 1, 2020.
Calgary, Canada's fastest growing major city, is vibrant and multicultural with a population of more than 1.2 million. Situated near the Rocky Mountains, Banff National Park and Lake Louise, Calgary offers great quality of life and outstanding recreational activities.
Dr Marie-Catherine Vozenin
Starting date: immediately; Contact: marie-catherine vozenin@chuv.ch
My team at the CHUV/Lausanne has been the first to develop a novel modality of radiotherapy called FLASH radiotherapy (FLASH-RT) that has the potential to revolutionize radiotherapy treatment in the near future, making it safer and more efficient. Using various biological studies, we have shown that FLASH-RT was able to eliminate cancer cells without causing any collateral damages to the normal tissue whereas classical radiation therapy, used for the treatment of cancer patients, eliminates cancer cells but causes damages to the surrounding normal tissue and unwanted side effects. FLASH-RT treatment is delivered very quickly in microsecond whereas several minutes are required for a treatment with classical radiotherapy. This very short time of exposure protects the normal tissue and change the way biological tissues respond to FLASH-RT. While, we are in the process of translating FLASH-RT in clinical trials, we obtained 4 years funding from the Swiss National fund, Sinergia to investigate and characterize the response of tissues to FLASH-RT at the physical, chemical and biological level. This multidisciplinary project will involve 6 phD and post-doctoral fellows working together with permanent researchers.
Lausanne area is beautifully located on the Leman lake, at the edge of the Alps. The PhD student will evolve in the unique and stimulating scientific environment of the Swiss Cancer of Lausanne and will work in a multidisciplinary team, on one of the most innovative subject in Radio-Oncology. In addition to be working on the a novel FALSH-RT approach, The selected PhD student will work with an innovative biological model based on the use of zebrafish embryos. The candidate will be specifically be in charge of investigating the biological cascade and the reactive oxygen species contribution activated after FLASH irradiation along three main axis:
· H2O2 measurement in cell line and Hyper zebrafish.
· Regulation of antioxidant pathway by FLASH-RT.
· Impact of oxygen metabolisms on immune response in tumor and normal tissue.
Profile of the candidate: A strong biology background is needed (Master 2), knowledge in radiobiology and/or in free radical chemistry would be a plus but above all the candidate must be curious, open-minded and team player.
References
Montay-Gruel P et al., PNAS, 2019.
Bourhis et al., Radiother&Oncol, 2019, in press.
Vozenin et al., Clin Oncol, 2019.
Montay-Gruel P et al. Radiother&Oncol,. 2018 Aug 31.
Vozenin et al. Clin Can Res, 2018, Jun 6.
Montay-Gruel P et al. Radiother&Oncol, 2017, Sep;124(3):365-369.
Jaccard M et al. Med Phys, 2018.
Fouillade C et al. Bull Cancer. 2017 Mar.
Jaccard M et al. Med Phys, 44(2):725-735.
Petersson K et al. Med Phys, 2017, 44(3):1157-1167.
Favaudon V et al. Sci Transl Med. 2014 Jul 16; 6(245):245ra93.
A postdoctoral position in regenerative biology is available in the Roehl Laboratory starting this autumn. The project focuses on zebrafish tail regeneration and specifically on how regeneration is initiated after wound closure. The project builds upon our recent Nature Comms paper that identified a central role for Hedgehog signalling the initiation of regeneration. Some of the advanced technologies that will be used in this project are: light sheet microscopy and cre/lox transgenics to track regenerative cell migration; RNAseq analysis to identify early regenerative genes; CRISPR/Cas9 to analyse the role of candidate genes. The postdoc will join a large group of regeneration/developmental/stem cell biologists that are in the Bateson Centre/Department of Biomedical Sciences at the University of Sheffield. In the last REF assessment we were ranked #1 in the UK for Biomedical Research. We will consider applications from the UK as well as international candidates. Informal enquiries are encouraged and should be emailed to Henry Roehl along with a CV (h.roehl@sheffield.ac.uk).
References:
The Kelsh lab at the University of Bath (UK) is seeking both a postdoctoral fellow and a research assistant to work on a BBSRC-funded project on zebrafish neural crest fate specification. Together, you will combine single cell transcriptomics and sophisticated in vivo imaging to examine how and when individual cell fates are chosen. You will work closely in an interdisciplinary team with biomathematicians at both the University of Bath (Prof. Jon Dawes) and the University of Surrey (Dr Andrea Rocco) to develop and refine biologically-informed models of how neural crest fate specification works.
Applicants should have:
- A PhD (PDRA) or first degree (RA) in Genetics, Molecular Biology, Developmental Biology or related subject
- An interest in fate specification mechanisms and gene regulatory networks
- A collaborative and communicative personality, with a strong desire to work effectively within an interdisciplinary team
- Expertise in single cell transcriptomics, genetic manipulation or advanced imaging techniques (especially Lightsheet Microscopy) highly desirable
- Experience of model organisms, especially zebrafish, also an advantage
In addition to salary you will receive a generous annual leave entitlement and excellent development opportunities. The benefits package includes pension, childcare assistance and leisure facilities, and the lab, the Department and the University are committed to providing a supportive and inclusive working environment.
For informal enquiries, please contact Robert Kelsh at r.n.kelsh@bath.ac.uk
Please note that formal applications must be submitted via the links below.
For full details, please see:
https://www.bath.ac.uk/jobs/Vacancy.aspx?ref=CC6836
(PDRA)
and
https://www.bath.ac.uk/jobs/Vacancy.aspx?ref=CC6837
(Research Assistant)
Closing date for both positions is 14th July 2019.
Robert Kelsh
Professor of Stem Cell and Developmental Genetics, and Director of Research
Dept of Biology & Biochemistry and Centre for Regenerative Medicine
University of Bath
Claverton Down
Bath
BA2 7AY
UK
The Frazer lab at the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City seeks a post-doctoral fellow. We study lymphocyte leukemias & lymphomas using zebrafish models and in vitro tissue culture, with emphasis on the genetic events underlying oncogenesis and therapy resistance. My lab belongs to the Depts. of Pediatrics, Cell Biology, and Microbiology & Immunology, and the OUHSC Stephenson Cancer Center.
A fun, motivated, independent, and creative person is a perfect fit for our group of 8. I am committed to mentoring junior scientists to achieve their career goals. Projects developed as a post-doc can be taken upon leaving the lab. Applicants need a PhD and/or MD, and experience with zebrafish, genetics, and/or molecular biology are plusses.
OUHSC has a large campus with multiple schools (graduate, medical, dental, allied-health, nursing, etc.). Our lab is well-equipped, with strong core facilities available. We have an aquatic facility manager who coordinates fish care, breeding, IVF, etc., so you can focus on experiments.
Oklahoma City is the 27th largest US city (~1.3 million people) and Oklahoma’s capital. It has diverse cultures & ethnicities, as does our lab. OKC’s cost of living is very low, so post-docs have a high standard of living. Please contact me by email & attach your CV if you’d like to discuss the position further.
Kimble Frazer, M.D., Ph.D.
Children’s Hospital Foundation E.L. & Thelma Gaylord Chair
Associate Professor of Pediatrics, Section of Pediatric Hematology-Oncology
University of Oklahoma Health Sciences Center
There is a vacancy for a PhD position in molecular biology at the Department of Biological Science (BIO), Bergen, Norway. The position is part of the project "Investigation of algal toxins in regulating stress granule formation and cell survival via the neurodegenerative disease associated factor DJ-1". The position is for a fixed-term period of 3 years with the possibility of a 4th year with compulsory other work (e.g. teaching duties at the department). The position is financed by the University of Bergen (UiB).
About the project/work tasks
β-N-methylamino- Lalanine (BMAA) is a stress-inducing toxin, in which neurotoxicity is protected by the multifunctional protein DJ-1. BMAA is produced by cyanobacteria and dinoflagellates worldwide, and has been suggested to be an environmental risk factor in the development of Amyotrophic Lateral Sclerosis (ALS). DJ-1 was recently shown to co-localize with stress granules. Stress granules are pro-survival protective structures that assemble in response to a variety of environmental stresses and disassemble after the stress has resolved. The fellow doctor will focus to understanding the cellular mechanism(s) of BMAA neurotoxicity, how this relates to known ALS pathology, and how DJ-1 inhibits neurotoxicity. Experiments will be performed in cell lines and zebrafish to determine stress granule formation in response to BMAA. The involvement of stress granule regulation through DJ-1 will be investigated using a G3BP1 knock-out cell line and DJ-1 deficient zebrafish. RNA-protein pulldown and RNA-sequencing will be used to identify the mRNA interactome of DJ-1. The project will provide training in a multidisciplinary environment, developing skills in cell biology, molecular biology, zebrafish transgenesis and bioinformatics. Prof. KE Fladmark will be the main supervisor and Ass prof. S-N Grellscheid,and Prof. L Ebbesson will be co-supervisors for the project.
Qualifications and personal qualities:
. Applicants must hold a master's degree or the equivalent in molecular biology, or must have submitted his/her master's thesis for assessment prior to the application deadline. It is a condition of employment that the master's degree has been awarded.
. Experience with molecular neurobiology, CRISPR/cas9 methodology, relevant zebrafish techniques or live imaging is an advantage.
. Applicants must be able to work independently and in a structured manner, and demonstrate good collaborative skills.
. Applicants must be proficient in both written and oral English.
Personal and relational qualities will be emphasized. Ambitions and potential will also count when evaluating the candidates.
About the PhD position
The fellowship will be for a period of 3 years, with the possibility for a 4th year, consisting of 25 % compulsory work (e.g. teaching responsibilities at the department) distributed across the employment period. The 4th year is contingent on the qualifications of the candidate and the teaching needs of the department, and will be decided upon appointment.
About the research training
As a PhD candidate, you must participate in an approved educational programme for a PhD degree within a period of 3 years. A final plan for the implementation of the research training must be approved by the faculty within three months after you have commenced in the position. It is a condition that you satisfy the enrolment requirements for the PhD programme at the University of Bergen.
We can offer:
. a good and professionally challenging working environment
. salary at pay grade 51 (Code 1017/Pay range 20, alternative 9) in the state salary scale. This constitutes a gross annual salary of NOK 449 400. Further promotions are made according to length of service in the position.
. enrolment in the Norwegian Public Service Pension Fund
. a position in an inclusive workplace (IA enterprise)
. good welfare benefits
Your application must include:
. a brief account of the applicant's research interests and competence in methodology.
. a letter of motivation for the project
. the names and contact information for two referees. One of these should be the main advisor for the master's thesis or equivalent thesis
. CV
. transcripts and diplomas showing completion of the bachelor's and master's degrees, or official confirmation that the master's thesis has been submitted
. relevant certificates/references
. a list of any works of a scientific nature (publication list)
. any publications in your name
The application and appendices with certified translations into English or a Scandinavian language must be uploaded at Jobbnorge.
https://www.jobbnorge.no/en/available-jobs/job/171658/phd-position-in-molecular-biology
General information
For further details about the position, please contact Prof. Kari Espolin Fladmark, Department of Biological Science, phone: +47 55 584514.
The state labour force shall reflect the diversity of Norwegian society to the greatest extent possible. Age and gender balance among employees is therefore a goal. It is also a goal to recruit people with immigrant backgrounds. People with immigrant backgrounds and people with disabilities are encouraged to apply for the position.
We encourage women to apply. If multiple applicants have approximately equivalent qualifications, the rules pertaining to moderate gender quotas shall apply.
The University of Bergen applies the principle of public access to information when recruiting staff for academic positions.
Information about applicants may be made public even if the applicant has asked not to be named on the list of persons who have applied. The applicant must be notified if the request to be omitted is not met.
Further information about the employment process can be found here.
The Myopathy Research Team in at Monash University, Melbourne, Australia, is looking for a PhD student to work on an exciting new project, funded by Muscular Dystrophy Australia www.mda.org.au and supervised by Dr Tamar Sztal. The aim of the project is to study inflammation in Duchenne Muscular Dystrophy (DMD) and the effect on necrosis and regeneration.
Scholarships covering tuition fees and providing a living allowance of AUD$27,872 per year are available to both Australian and international students.
Monash University is the largest university in Australia and is consistently ranked in the top 100 universities in the world and is ranked in the top 50 for Biological Sciences. The School of Biological Sciences provides an outstanding scientific environment in which to undertake a PhD. It is home to world-renowned researchers in a range of biological disciplines providing a highly collaborative and supportive environment. We have a large and dynamic postgraduate community with students drawn from a wide range of nationalities, cultures, and backgrounds. This creates a productive scientific environment as well as an active social atmosphere.
We are looking for highly motivated and enthusiastic applicants with experience in molecular biology, developmental biology/genetics, and, ideally, someone who has previously worked with zebrafish.
The applicant must have a MSc (research) or BSc or equivalent degree in genetics, developmental biology, or related discipline including a research project of at least 6 months full time (or equivalent) duration.
Minimum English language requirements; IELTS 6.5 overall (no less than 6 in any category), TOEFL ibt 79 (at least 21 writing, 18 for speaking, 13 reading, 12 listening); or to be from, or have a tertiary qualification with at least 2 years study from, a country with English as the primary language.
Interested applicants should send a copy of their academic transcripts and CV in the first instance to tamar.sztal@monash.edu by the 30th June 2019. Selected applicants will then be invited to submit a full application.
A postdoctoral position in nutritional epigenetic mechanisms is available in the laboratory of Dr. Peggy Biga in the Department of Biology at the University of Alabama at Birmingham.
The lab is interested in understanding epigenetic mechanisms underlying maternal effect on offspring, with an emphasis on how maternal diet influences offspring metabolic and growth physiology in relation to epigenetic regulatory mechanisms. Using cellular, molecular, genomic, and whole organism approaches, our research focuses on 1) understanding the molecular basis of maternal effect on metabolic health, 2) discovery of epigenetic targets for maternal dietary influence, and 3) understanding the transgenerational effects of maternal diet. Our lab uses fish species as our model organisms, so experience/background in fish biology is a plus. The postdoctoral scientist will have the opportunity to work with rainbow trout and zebrafish models to understand maternal diet effects on offspring performance.
We are looking for a scientist with demonstrated independence, and passion for epigenetics, genomics, and comparative biology. Prior experience in epigenetics or genomics research is a plus but not essential. The successful candidate will have the opportunity to establish multidisciplinary collaborations and develop state-of-the-art genetic/genomic tools (ChIP-seq, RRBS) and utilize both in vivo and in vitro methodology.
Website: https://www.uab.edu/cas/biology/people/faculty/peggy-biga
Desired Qualifications
- Candidates must have a doctoral degree (Ph.D.) in zoology, biology, molecular biology, epigenetics, genetics or genomics, or related field.
- Preference will be given to creative and motivated candidates with experience in nutritional and growth physiology, primary cell culture, epigenetics, and/or larger-scale genomics analyses.
- The ideal postdoctoral candidate will be dedicated to basic research with strong analytical and communication skills. The fellow is expected to collaborate with colleagues inside and outside the laboratory
- The ideal candidate will also serve as a leader within the laboratory, so previous mentoring and leadership experience will be given preference.
To apply: Please send the following to pegbiga@uab.edu:
- A cover letter summarizing research interests and accomplishments; describing how your skills, training, and experience fit with the lab; and explain how this work would fit with your future career goals;
- A complete CV with a publication list;
- Contact information for three references
Start date: July 2019 and later.
About the University
UAB is committed to the development and success of outstanding postdoctoral scientists. The Office of Postdoctoral Education (OPE) at UAB provides mentoring and career guidance. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB. There is access to several outstanding interdisciplinary programs and core facilities. The Birmingham area provides a metropolitan lifestyle, excellent schools, comfortable climate, and low cost of living.
UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity, and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans. For more information on Equal Opportunity and Affirmative Action at UAB, visit the UAB Office of Diversity, Equity and Inclusion. Or contact the office at 701 20th Street South, AB 336, Birmingham, AL 35294-0103.
About Our Postdoc Office
UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines, including dentistry, engineering, health professions, medicine, natural sciences and mathematics, public health, optometry, and social and behavioral sciences. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The OPE strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They may also have the right to participate in the university's 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.
Contract Type: Fixed Term Contract
The University of Luxembourg is a multilingual, international research University.
The Luxembourg Centre for Systems Biomedicine invites applications for
Associate Professor Position in Complex and Systems Genetics (M/F) at the Luxembourg Centre for Systems Biomedicine (LCSB)
- Ref: I1-50011560
- Full-time position
- Tenure-track for 5 years
- Earliest starting date: January 2020
About the University of Luxembourg and LCSB
Founded in 2003, the University of Luxembourg is the only public university of the Grand Duchy of Luxembourg. It is a multicultural and modern European research university with a personal atmosphere. With an emphasis on interdisciplinary research, the University of Luxembourg strives for international excellence as well as regional relevance. The University of Luxembourg offers a competitive package and an international research and teaching environment.
The newly recruited professor will join the LCSB - an interdisciplinary research centre within the University of Luxembourg. At LCSB we accelerate biomedical research by closing the link between systems biology and medical research. Collaborations between biologists, medical doctors, computer scientists, physicists, engineers and mathematicians offer new insights in complex systems essential for understanding principal mechanisms of disease pathogenesis and for developing new tools in diagnostics and therapy.
Your Role
As an Associate Professor at the University of Luxembourg you will:
- conduct research at the highest scientific level
- set up and develop your own research group in the field of complex and systems genetics
- be responsible for establishing a competitive research programme in complex and systems genetics with a focus on developing animal models for neurodegenerative diseases (preferentially Parkinson’s or Alzheimer disease), investigating gene to environment interactions and reaching out to computational approaches
- become the scientific leader of the state-of-the-art fish and mouse facilities of LCSB
- successfully attract external research grants from national and international sources
- lead interdisciplinary research by reaching out to the experimental, computational and clinical research groups within the collaborative environment of the University and LCSB
- interact and collaborate with other groups within the Luxembourg and the international research community
- be engaged in teaching courses for the Master in Systems Biology and upcoming medical education program as well as supervising and training of PhD students and mentoring of postdocs
Your Profile
- a Ph.D. in relevant field with documented background in complex and systems genetics
- an excellent research record in complex and systems genetics proven by high-level publications, conference presentations, and participation in international research collaborations
- experience in animal studies as well as design and conduct of experiments – practice with different animal models is a plus
- Proven expert knowledge of the principles, regulations and professional ethics related to animal biomedical research including necessary qualification and training certificates (FELASA or equivalent)
- experience in interdisciplinary research, systems and computational biology and/or willingness to emerge in this highly interdisciplinary environment
- proven leadership skills, including personnel and budget management skills
- experience in acquiring and managing research projects
- teaching experience at the undergraduate and the postgraduate level as well as supervisory skills
- strong interpersonal and communications skills
- proficient in English and in one of the two official languages of Luxembourg: French or German
- the University encourages its staff to learn the other official language and provides access to language courses to this end
We offer
- A 5-year tenure track with evaluation and possible promotion to full professor
- Fully funded position with competitive remuneration and attractive group budget
- Highly engaged and motivated staff in a positive and dynamic international and interdisciplinary working environment
- Access to state-of-the-art animal facilities: New rodent facility opened in 2018 (including SOPF breeding area, SPF experimental areas and Germ-free units) and the aquatic facility opened in 2016 equipped with cutting-edge semi-automated installations.
Further Information
Candidates are welcome to send their complete application per e-mail to LCSB.recruitment@uni.lu by August 15, 2019 at the latest. Please mention the job post reference in the subject field.
The following documents (in English) are requested to be submitted:
- A detailed curriculum vitae with a list of publications, courses taught, research grants, industry collaborations and experience, patents, as well as management and administrative positions held
- A cover letter including a statement highlighting scientific, educational, and other activities of particular significance for this position
- A short research statement presenting future research lines
- A list of three references including their contact information and current positions. Please indicate their relationship to you; (the referees will be contacted only upon approval from the candidate)
- Any additional material highlighting significant publications, success in obtaining research funding, industry contacts and collaborations, experience in management positions within a university or research centre, as well as other relevant qualifications and achievements are appreciated
The position at the Associate Professor level follows Luxembourg’s tenure-track scheme. An initial appointment on a fixed-term contract is foreseen. Upon successful evaluation of the projects, the candidate may be offered a permanent position and the possibility of promotion to Full Professor.
In addition to the above-mentioned application procedure, you might also complete the online application by clicking on “apply online” below. This is, however, not obligatory, and will not have any impact on the selection process.
Contact
For questions please contact:
Prof. Rudi Balling
Director of the Luxembourg Centre for Systems Biomedicine
Campus Belval | Biotech II
6, avenue du Swing
L-4367 Belvaux
e-mail: rudi.balling@uni.lu
All applications will be handled in strictest confidence.
The University of Luxembourg is an equal opportunity employer.