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ECOLE NORMALE SUPERIEURE

Laboratoire de Physique et Institut de Biologie

associé au CNRS et aux Universités Paris VI et VII

46 rue d’Ulm, Paris 75005

 

                                                                                               

 

 

Post-doctoral position available at ENS

 

A 2-3 years post-doctoral position is available at the ENS, Paris, to study the initiation and growth of cancer from a single cell in zebrafish. The idea is to use the optogenetic tools developed in the host lab to turn on one (or a few) oncogenes (or off some tumor suppressor genes) in single cells of a zebrafish larvea.  The probability of tumorigenesis will be measured and the genetic analysis of cancer developing cells vs non-cancer developing ones will be conducted.

 

For this project we are looking for a smart, independent and driven person with demonstrated experience in zebrafish: micro-injection, transgenesis, microscopic observations, ISH and genetic analyses.

Knowledge of image analysis (ImageJ) and computer programming (R, Matlab, LabView) favored.

The person will be paid a net post-doctoral salary of about 2800€ (depending on experience). 

 

Appropriate candidates should send their CV and three letters of recommendation to David Bensimon (david@lps.ens.fr) .

 

References:

  1. “Optical control of tumor induction in the zebrafish”, Z.Feng, S.Nam, F.Hamouri, I. Aujard, B.Ducos, S.Vriz, M.Volovitch, L.Jullien, S.Lin, S. Weiss and D.Bensimon, Sci.Rep. 7, 9195 (2017)
  2.  Control of protein activity and gene expression by cyclofen-OH uncaging”, W.Zhang, F.Hamouri, Z.Feng, I. Aujard, B. Ducos, S. Ye, S.Weiss, M.Volovitch,  S.Vriz, L.Jullien and D.Bensimon, ChemBioChem 19,1-8 (2018)

 

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