One postdoctoral position is available at the Nicoli Lab, Department of Genetics and Internal
Medicine, Yale University, New Haven, CT USA.
The goal of our laboratory is to combine RNA-based mechanisms, genomics, and genetics in
embryonic development to uncover new endothelial cell behaviors in vascular development and
homeostasis. Our laboratory contributed to this research field with several publications available at
nicolilab.com (most relevant for this job posting are Kasper bioRxiv 2019, Moro Nat. Cell Bio. 2019,
Kasper Dev. Cell 2017, Narayanan Sci. Rep. 2016)
Area of interests in the Nicoli Lab:
1) Define RNA-based regulations occurring during mechanotransduction. The central question is to
understand how translational and regulation of biomechanical genes control cell behaviors dictated by
the extracellular matrix and/or blood flow-hemodynamics.
2) Define the functional effect of multigene miRNA families on developing vascular treats. The central
question is to assign function to complex miRNA genes using an endothelial single cell phenotypic
screening in zebrafish miRNAs knockouts.
3) Define Cis-regulatory RNAs that determine vascular cell behaviors. The central question is to
decode sequences on the RNA that control common or tissue specific homeostatic endothelial cell
Candidates with excellent molecular biology and/or microscopy skills will be considered.
Computational skills are preferable but not necessary. Candidates are required to have strong
interpersonal skills and outstanding written and spoken English to collaborate with a diverse team of
scientists. Qualified candidates should have recently accomplished their Ph.D. degree (possibly no
more than 1 year).
Candidates should send their Curriculum Vitae and a cover letter summarizing:
- A description of accomplishments.
- Research interests in RNA and/or Development and/or Vascular Biology.
- Contact information for three references to: Stefania Nicoli, Ph.D. firstname.lastname@example.org