Blog from April, 2019

To expand our lab’s team at our future location at the University of Colorado School of Medicine, Section of Developmental Biology (starting summer 2019), we are looking to recruit Postdocs.

Our lab’s research aims to elucidate the molecular mechanisms of cell fate determination during the formation of universal features of the vertebrate body plan. As main paradigm, we study the developmental emergence and patterning of the lateral plate mesoderm (LPM), the elusive joint origin of the cardiovascular, blood, kidney, and limb lineages.

We study the LPM and its molecular regulation using advanced transgenic approaches, gene-regulatory element discovery, genome editing, cross-species comparisons, and lightsheet imaging using the zebrafish as principal model. Our work provides an interface to developmental biology, evo-devo, and disease modeling projects that we also pursue with an international network of collaborators. A special interest are the genetic causes of congenital cardiac disease. 

Interested applicants have:

* a PhD degree in developmental biology, genetics, molecular biology, biochemistry, or related disciplines;
* model organism experience, zebrafish experience preferred;
* an interest in cell fate determination, cardiovascular development, transcriptional regulation, live imaging, transgenesis, genome editing, and disease modeling;
* ideally prior expertise in any or all of SPIM/lightsheet imaging, molecular cloning, cross-species experiments, chromatin-based techniques;
* a collaborative, communicative, and team-oriented personality.

We offer an international, interactive, inclusive, and collaborative lab environment with access to state-of-the-art imaging resources and facilities. Our lab is located at the Anschutz Medical Campus within the Department of Pediatrics, Section of Developmental Biology, and embedded in a growing framework of basic and clinically oriented research labs.

Initial positions are funded for 2-3 years, with possibility of extension. Starting date negotiable and earliest in August 2019. Application for third-party and independent funding is strongly encouraged and supported.

Interested? Apply with Cover Letter, Resume/CV, List of References through CU Careers online, only online applications can be considered:
https://cu.taleo.net/careersection/2/jobdetail.ftl?job=16182

For more info, get in touch with Christian Mosimann (christian.mosimann@ucdenver.edu) about the framework and possible projects (please refer to Position #760630– Requisition #16182). Follow @chrmosimann on Twitter for updates.

Come join us in Denver, Colorado!

The Juntti Lab at the University of Maryland, located just outside Washington DC, studies the neuroscience and evolution of social behavior. We use cutting-edge technologies in molecular genetics, neuroanatomy, computer vision, pharmacology, and more to solve some of the most exciting questions in biology. Our model is the family of cichlid fish, which exhibit fascinating and variable social behaviors. We regularly use CRISPR and transgenesis to test mechanisms that regulate these interactions. We’re looking for a motivated and organized candidate who will collaborate in the design and execution of experiments, and will facilitate operations in the lab. 

 

See our lab website for more information about cichlids and us: biology.umd.edu/scott-juntti

 

Position is available beginning Summer of 2019.

 

Responsibilities Include:

  • PCR genotyping
  • CRISPR/Cas9 gene editing
  • Embryo microinjection
  • Coordinate fish colony maintenance
  • Ordering supplies
  • Plan and perform experiments in support of research projects
  • Help with general lab maintenance as needed; maintain lab stocks, manage chemical inventory and safety records
  • Must be comfortable standing on stepladders and lifting 50 pounds
  • Help orient and train new staff or students
  • Research techniques may include: Immunohistochemistry, in situ hybridization, microscopy, behavior analysis, computational biology

 

Education & experience required:

  • Bachelor's degree in related scientific field
  • Lab experience outside of coursework
  • General computer skills and ability to quickly learn and master programs and scientific applications

 

Desired qualifications

  • Experience working with animal models, bonus for prior fish work
  • Advanced neuroscience and/or molecular biology work
  • Able to manage overlapping projects and deadlines effectively
  • Ability to work under deadlines with general guidance
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work
  • Experience with immunohistochemistry, in situ hybridization, tissue culture, cloning, coding languages are all major plusses.

 

About the environment

The University of Maryland is located in College Park, 6 miles from Washington, DC. It is easily accessible by Metro or car. We are housed in the Department of Biology, a stimulating group of scientists studying everything from ecology to evolution to neural circuits. You will be part of building a lab into an exciting environment for science and supportive environment for training researchers.

 

Compensation

Salary is commensurate with experience. UMD offers excellent benefits: https://uhr.umd.edu/benefits/

 

To apply: Please send a resume with references and a cover letter to sjuntti@umd.edu briefly addressing the following questions: How do your skills, training, and previous experience fit the job requirements? Why are you interested in this position? How would this work fit with your future career goals? What excites you most about science?

The Mount Desert Island Biological Laboratory, located in Bar Harbor, Maine, is an independent biomedical research institution undergoing rapid growth and development. We are seeking outstanding scientists for recruitment at the Assistant Professor level. Successful applicants will be expected to develop research programs focused on the biology of aging and/or regeneration using state-of-the-art genomic, genetic and molecular approaches and utilizing non-mammalian model organisms such as C. elegans and zebrafish. New scientific approaches and technologies that could have a significant impact on these areas are also of interest as is a commitment to translating relevant discoveries into new tools and therapies. Candidates must possess a Ph.D. or M.D. degree, have a strong record of continuous research productivity, and have either active funding or clearly demonstrated potential for independent funding.

The MDI Biological Laboratory provides a uniquely collaborative and multidisciplinary research environment, outstanding scientific resources, and at least 80% protected time for development and maintenance of independent, externally funded faculty research programs. Start-up packages and salary are highly competitive and commensurate with current rank and experience. Successful candidates will have appointments in the Davis Center for Regenerative Biology and Medicine, an NIH-funded Center of Biomedical Research Excellence, and the opportunity for adjunct appointments at neighboring academic institutions, including the University of Maine.

Please apply electronically at https://www.mdibl.org/about/careers. Review of applications will continue until the positions are filled. If you need assistance with completing the online application or uploading documents please email ppcolar@mdibl.org. MDIBL is an Affirmative Action/Equal Opportunity Employer committed to excellence through diversity. Women and Minorities are encouraged to apply.

 

http://www.mdibl.org

 

 

Postdoctoral positions, University of Michigan, Ann Arbor, MI

 

NIH R01-funded postdoctoral positions are available in “clinically directed basic research” in the field of blood clotting disorders. Disorders of coagulation underlie major medical problems, including pathologic clotting (thrombosis), hemorrhage, heart attack, and stroke. Although we have an in depth understanding of the coagulation cascade, we are often unable to predict an individual patient's risk with any useful degree of accuracy due to modifier genes. Knowledge of such modifier genes will improve diagnosis and classification of blood coagulation disorders, identify potential targets for therapy, and further our understanding of the underlying biology of hemostasis and thrombosis.

 

We have developed multiple zebrafish models of human blood clotting disorders (hemophilia, von Willebrand disease, platelet defects, thrombosis) through genome editing with zinc finger nucleases, TALENs, and CRISPR. Projects include dissection of extended coagulation factor pathways and thrombocyte (platelet) function in vivo, mechanistic studies of oral contraceptive-induced thrombosis, sensitized ethylnitrosourea (ENU) mutagenesis followed by next generation sequencing for modifier gene identification, and high throughput small molecule screens to discover novel pro- and anticoagulant therapeutics.

 

Required qualifications:

 

  1. PhD, MD, or equivalent with research experience in molecular biology, genetics, developmental biology, biochemistry, chemistry or related health field.
  2. Working knowledge of the principles of molecular biology.

 

Desired qualifications:

 

  1. Research experience in hemostasis/thrombosis, zebrafish, mouse, or other animal models.
  2. Experience in bioinformatics, computer programming, familiarity with Linux, and analysis of next generation sequencing data.

 

Please send a CV/resume and any additional information to Jordan Shavit (jshavit@umich.edu). For more information see http://www.shavitlab.org/

RESEARCHER II
 - (T61204)
 
Under minimal supervision, to set up and perform routine and established lab procedures in support of lab goals. To collect, enter and summarize data. To monitor results and report unusual outcomes.

We are looking for two (2) Research Assistants to join the Thyme laboratory in the Department of Neurobiology at University of Alabama at Birmingham (UAB). The ideal candidate would have a BS or BA degree in the field of biological sciences, with preferably a year or more of relevant research experience.

The Thyme lab uses zebrafish as a model system to understand mechanisms underlying psychiatric and neurodevelopmental disease. See an example of recent work at https://www.biorxiv.org/content/10.1101/360677v2. The candidate will assist with experiments potentially utilizing the following techniques: molecular biology (PCR, cloning), biochemistry (protein purification), zebrafish genome-editing, zebrafish line maintenance, antibody staining, RNA in situ analysis, high-resolution imaging, high-throughput larval behavior, drug screens, and transcriptomics (bulk and single-cell RNA-seq).

Candidate responsibilities will include but not limited to:

Collecting, organizing and reporting research data
Assisting in the design of experiments
Maintaining laboratory supplies and equipment
Assist and instruct/mentor others in basic laboratory techniques

Essential Skills:

Organization, critical thinking, communication, and attention to detail
Standard lab notebook practices

$27,000 - $48,900

Start dates between July 1 and September 1 2019 are possible.

https://uab.taleo.net/careersection/ext/jobdetail.ftl?job=T61204

Contact information: sthyme@uab.edu

One postdoctoral position is available at the Nicoli Lab, Department of Genetics and Internal

Medicine, Yale University, New Haven, CT USA.


The goal of our laboratory is to combine RNA-based mechanisms, genomics, and genetics in

embryonic development to uncover new endothelial cell behaviors in vascular development and

homeostasis. Our laboratory contributed to this research field with several publications available at

nicolilab.com (most relevant for this job posting are Kasper bioRxiv 2019, Moro Nat. Cell Bio. 2019,

Kasper Dev. Cell 2017, Narayanan Sci. Rep. 2016)


Area of interests in the Nicoli Lab:

1) Define RNA-based regulations occurring during mechanotransduction. The central question is to

understand how translational and regulation of biomechanical genes control cell behaviors dictated by

the extracellular matrix and/or blood flow-hemodynamics.


2) Define the functional effect of multigene miRNA families on developing vascular treats. The central

question is to assign function to complex miRNA genes using an endothelial single cell phenotypic

screening in zebrafish miRNAs knockouts.


3) Define Cis-regulatory RNAs that determine vascular cell behaviors. The central question is to

decode sequences on the RNA that control common or tissue specific homeostatic endothelial cell

behaviors.


Candidates with excellent molecular biology and/or microscopy skills will be considered.

Computational skills are preferable but not necessary. Candidates are required to have strong

interpersonal skills and outstanding written and spoken English to collaborate with a diverse team of

scientists. Qualified candidates should have recently accomplished their Ph.D. degree (possibly no

more than 1 year).


Candidates should send their Curriculum Vitae and a cover letter summarizing:

- A description of accomplishments.

- Research interests in RNA and/or Development and/or Vascular Biology.

- Contact information for three references to: Stefania Nicoli, Ph.D. stefania.nicoli@yale.edu

The Giraldez laboratory at Yale University is seeking to recruit a highly qualified Associate Research Scientist as a long-term scientist in the laboratory (www.giraldezlab.org). Prerequisites for appointment on the research scientist track include a doctoral degree and relevant postdoctoral experience. 

The successful candidate will be highly-motivated scientist with excellent organizational, mentoring and leadership skills. They will be responsible for coordinating the overall scientific operations of the Giraldez lab and will provide critical training and mentoring to individual lab members. In addition, the successful candidate will have the opportunity to participate in multiple research projects and drive a scientific project aligned with the major interests of the laboratory. The successful candidate will have the following attributes:


• A doctoral degree and relevant postdoctoral experience
• Excellent interpersonal and communication skills
• Excellent organizational skills and attention to detail
• Solid publication record and the ability to drive long-term, successful research projects 
• Expertise in one or more of the following: molecular biology, chromatin biology, developmental biology, genomics, and/or imaging

This appointment can be renewed indefinitely provided the need for the position continues, the funding for the position is available, and the expectations for performance are met.

To apply to this position please submit the following using the Interfolio Link: https://apply.interfolio.com/50482

1) A one-page cover letter describing your motivation for the position, research experience, and relevant mentoring/organizational experience, 

2) biosketch or CV, 

3) three letters of references 

4) PDFs of three publications 

 

For inquiries please contact hiba.codore@yale.edu. Please include “Associate Research Scientist” in the subject of the email.

 

Applications are now open and will be considered on a rolling basis. Salary will be commensurate with experience and the appointment includes an attractive benefits package in line with an appointment in the research track within the Yale School of Medicine

 

Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.)


Minimum qualification: Bachelor’s degree plus at least 3 years of experience working with zebrafish

 

The ideal candidate could have extensive zebrafish husbandry experience, or could be a PhD scientist with zebrafish experience who would rather run a fish facility than run a lab – we are open to all possibilities.

 

The facility includes 24 Tecniplast racks with 3 robotic feeders, 8 Aquaneering racks and 5 stand-alone Pentaire (Aquatic Habitats) racks. The facility supports all PIs working with zebrafish at Baylor College of Medicine.

 

Duties include supervising and training caretakers & technical staff, interfacing with veterinarians, maintaining equipment, monitoring fish health and embryo survival, providing support to researchers.

 

The position includes generous salary, benefits and relocation expenses.

 

For inquiries, please contact Daniel Gorelick, Assistant Professor, Center for Precision Environmental Health (gorelick@bcm.edu) or Mary Dickinson, Professor & Associate Dean for Research (mdickins@bcm.edu

 

The Department of Pathology at University of Washington Medical School is seeking a highly motivated research fellow to work in the laboratory of Dr. Eleanor Chen. The Chen lab uses gene editing (CRISPR) technology, functional genomics, cell-based and animal models to study disease pathogenesis and discover translational applications for pediatric rhabdomyosarcoma, a devastating pediatric soft tissue cancer.  As part of the interactive network of researchers in the Department of Pathology at the University of Washington Medical School, the individual will be integrated into both the medical and research community.  The research fellow will also have the opportunity to interact with prominent researchers at the Stem Cell Institute as well as Fred Hutchinson Cancer Research Center.

Research will focus on integrating the zebrafish genetic model, mammalian in vitro and in vivo work (e.g. loss-of-function and gain-of function characterization in human cell lines and xenograft mouse models) as well as functional genomics to better understand molecular and cellular mechanisms underlying human cancer. The ultimate goal of the research is to develop novel therapeutic insights. Projects will include

            - Functional genomics studies (RNA and ChIP sequencing to identify and characterize cancer essential genes)

            - Molecular and cellular characterization of oncogenic/tumor suppressor gene functions

            - Live imaging and transplantation studies of fluorescently-labeled zebrafish tumors to characterize cellular events during tumor progression

            - High-throughput gene/drug target discovery studies (e.g. CRISPR screens and chemical screens)

            - Tumor xenograft mouse models for genetic or therapeutic characterization of promising therapeutic targets. 

Required qualifications:

            - A successful candidate should have a degree in PhD and/or MD

            - Productive scientific contributions through publication of high-impact papers

Desired qualities:

            - A candidate with background in cancer research and/or animal models is highly desired but not required.

            - Advanced skills in any of the following areas: human cell line/mouse/zebrafish work, functional genomics (RNA/ChIP sequencing), bioinformatics analysis, gene editing (CRISPR) technology and molecular biology.

For additional information about research in the Chen lab, please refer to recent publications from the lab:

a. Phelps M, Chen E. Zebrafish Rhabdomyosarcoma. Adv Exp Med Biol. 2016;916:371-89. doi: 10.1007/978-3-319-30654-4_16. Review. PubMed PMID: 27165362.

 

b.  Phelps MP, Bailey JN, Vleeshouwer-Neumann T, Chen EY. CRISPR screen identifies the NCOR/HDAC3 complex as a major suppressor of differentiation in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016.

 

c. Phelps MP, Yang H, Patel S, Rahman MM, McFadden G, Chen E. Oncolytic Virus-Mediated RAS Targeting in Rhabdomyosarcoma. Mol Ther Oncolytics. 2018 Sep 15;11:52-61.

 

Lab website:

http://faculty.washington.edu/eleanor2

 

 If interested, please send a CV and 3 references of contact to Dr. Eleanor Chen ( eleanor2@uw.edu or echen791@gmail.com).  Salary will be competitive with NIH Fellowship pay scales.  Position start date is negotiable.

 

 

Faculty Research Assistant

file:///Users/jonathanknight/Library/Containers/com.apple.mail/Data/Library/Mail%20Downloads/F63E0B41-14A8-4D71-AB9D-17D51F01135E/Oregon%20State%20University%20Portal%20%20%20Faculty%20Research%20Assistant.htm

When applying you will be required to attach the following electronic documents: 1) A resume/CV; and 2) A cover letter indicating how your qualifications and experience have prepared you for this position. You will also be required to submit the names of at least three professional references, their e-mail addresses and telephone numbers as part of the application process. For additional information please contact: Mary Fulton at mary.fulton@oregonstate.edu OSU commits to inclusive excellence by advancing equity and diversity in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community. This position is designated as a critical or security-sensitive position; therefore, the incumbent must successfully complete a criminal history check and be determined to be position qualified as per OSU Standard 576-055-0000 et seq. Incumbents are required to self-report convictions and those in youth programs may have additional criminal history checks every 24 months. Offers of employment are contingent upon meeting all minimum qualifications including the criminal history check requirement. This position requires driving a university vehicle or a personal vehicle on behalf of the university; therefore, the incumbent must successfully complete a motor vehicle history check, possess and maintain a current, valid driver's license in their state of residence, be determined to be position qualified and self-report convictions as per University Policy 05-030 et seq. Offers of employment are contingent upon meeting all minimum qualifications including the motor vehicle check requirement.

Position Details



Position Information
DepartmentMicrobiology (Ag) (AMB)
Position TitleFaculty Research Assistant
Job TitleFaculty Research Assistant
Appointment TypeAcademic Teaching/Research Faculty
Job LocationCorvallis
Position Appointment Percent100
Appointment Basis12
Faculty StatusRegular
Tenure StatusFixed-Term
Pay MethodSalary
Recommended Full-Time Salary RangeSalary is commensurate with education and experience.
Position Summary

The Department of Microbiology invites applications for a full-time (1.0 FTE), 12-month, Fixed-Term Faculty Research Assistant position. Reappointment is at the discretion of the Department Head.

This position will conduct research and maintain fish relating to a project on investigating various projects pertaining to infectious diseases in Dr. Kent’s program. Presently emphasis for this position will be directed toward investigations on infectious diseases of fish, including microsporidia, parasitic nematodes and copepods, and bacterial pathogens such as Mycobacterium spp. or Aeromonas salmonicida.

The employee must be able to maintain populations of fishes used for transmission experiments and fish species may include trout, zebrafish maintained either on the main campus, the Fish Performance and Genetics Laboratory or the Aquatic Animal Health Laboratory. The employee will oversee four fish laboratories in Nash Hall, including oversight of daily water systems, supervision of students regarding care of fishes, compliance with OSU IACUC and BioSafety requirements, ordering appropriate supplies, and interfacing with Facilities on maintenance and repairs of these systems.

The employee must be able to necropsy fish and isolate pathogens (including some that may infect humans). The employee will characterize pathogens using phenotypic and molecular methods. The employee will also supervise undergraduate and graduate students that will assist with maintaining fish. The above tasks are carried out with minimal supervision, including possible work off the main campus. Ongoing and new specific tasks are reviewed with the supervisor on a weekly basis.

Position Duties

30% Assist with research: Conduct necropsies on fish and process samples as appropriate for future diagnostic evaluation. Run PCR analysis of fish tissues to identify the presence of pathogens. Isolate and identify bacterial pathogens from fish. Identify and record specific pathologic changes or pathogens in histologic sections following specific training and instruction by supervisor.

25% Assist with Research: Establish and maintain in vivo transmission studies with fish. This include maintenance of stock infected and pathogen free fish, and occasional transport of fish from the Sinhubber Laboratory at OSU or ZIRC at University of Oregon.

20% Organize and maintain documentation for laboratory, including compliance records, chemical inventory, IACUC documents, training records, etc.

15% Analyze data and prepare scientific reports

10% Supervise and plan work for student assistants

Minimum/Required Qualifications

BSL-2 training.

Formal training if fish husbandry, fisheries and/or aquaculture.

Experience in maintaining fish in experiments, fish necropsy procedures, establishing and conducting in vivo transmission studies with fishes, bacteriology (culture and biochemical identifications).

Master’s degree in Life Sciences discipline with 2 years experience conducting biomedical research with laboratory animals. Or a Bachelor degree in Life Sciences with 5 years experience conducting biomedical research with laboratory animals.

This position is designated as a critical or security-sensitive position; therefore, the incumbent must successfully complete a criminal history check and be determined to be position qualified as per OSU Standard 576-055-0000 et seq. Incumbents are required to self-report convictions and those in youth programs may have additional criminal history checks every 24 months. Offers of employment are contingent upon meeting all minimum qualifications including the criminal history check requirement.

This position requires driving a university vehicle or a personal vehicle on behalf of the university; therefore, the incumbent must successfully complete a motor vehicle history check, possess and maintain a current, valid driver’s license in their state of residence, be determined to be position qualified and self-report convictions as per University Policy 05-030 et seq. Offers of employment are contingent upon meeting all minimum qualifications including the motor vehicle check requirement.

Preferred (Special) Qualifications

Bachelor’s or Master’s in microbiology, fish care technology.

Person with experience with zebrafish models of infection and working with BSL-2 pathogens is preferred.

Working Conditions / Work Schedule

Microbiology laboratory and aquatic vivaria. Typically 8-5, but occasional after hours and weekends as required for specific experiments

This position requires a clear and unambiguous commitment to compliance of all National Collegiate Athletic Association (NCAA) regulations for Division I (FBS) universities.No
Posting Detail Information
Posting NumberP02886UF
Number of Vacancies1
Anticipated Appointment Begin Date07/01/2019
Anticipated Appointment End Date06/30/2020
Posting Date04/04/2019
Full Consideration Date
Closing Date04/18/2019
Indicate how you intend to recruit for this searchCompetitive / External - open to ALL qualified applicants
Special Instructions to Applicants

When applying you will be required to attach the following electronic documents:

1) A resume/CV; and

2) A cover letter indicating how your qualifications and experience have prepared you for this position.

You will also be required to submit the names of at least three professional references, their e-mail addresses and telephone numbers as part of the application process.

For additional information please contact: Mary Fulton at mary.fulton@oregonstate.edu

OSU commits to inclusive excellence by advancing equity and diversity in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community.

This position is designated as a critical or security-sensitive position; therefore, the incumbent must successfully complete a criminal history check and be determined to be position qualified as per OSU Standard 576-055-0000 et seq. Incumbents are required to self-report convictions and those in youth programs may have additional criminal history checks every 24 months. Offers of employment are contingent upon meeting all minimum qualifications including the criminal history check requirement.

This position requires driving a university vehicle or a personal vehicle on behalf of the university; therefore, the incumbent must successfully complete a motor vehicle history check, possess and maintain a current, valid driver’s license in their state of residence, be determined to be position qualified and self-report convictions as per University Policy 05-030 et seq. Offers of employment are contingent upon meeting all minimum qualifications including the motor vehicle check requirement.

Supplemental Questions

Required fields are indicated with an asterisk (*).

Documents Needed to Apply


Required Documents

  1. Resume
  2. Cover Letter

Optional Documents

Copyright ©2018 Oregon State University
Disclaimer
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Notice of Availability:
In compliance with the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act, Oregon State University publishes Annual Security and Fire Safety Reports for each of the four Oregon State campuses: CorvallisCascadesHMSCOSU at EOU. These reports include current security policies plus crime and fire statistics for the previous three calendar years. Contact information for various campus and community resources related to crime prevention and survivor assistance is in the body and appendix of the reports. 

Paper copies for the Corvallis campus are available at 200 Cascade Hall, 601 SW 17th St., Corvallis, OR. If you prefer, you may request a copy by emailing HR.Compliance@oregonstate.edu. This report is available without charge.

Department Summary
Aquatic Animal Care Services (AqACS) is a Research Core Facility supported by the Vice President for Research and Innovation. The mission of Aquatic Animal Care Services is to support researchers using aquatic and semi-aquatic animal models, primarily fish, to study vertebrate genomics and vertebrate development by employing expert husbandry techniques, by supplying efficient and timely services, and by fostering a helpful, cooperative environment. The most prevalent fish model at the University of Oregon is the zebrafish (Danio rerio). Any research investigator with a sponsored project requiring the use of aquatic animals may use the facilities and animals hosted by AqACS, provided the project and its personnel follow all the federal, state, and university policies and procedures on the use of aquatic animals. Currently, AqACS supports 10 investigator laboratories, including all postdoctoral associates, graduate students, undergraduate students, and visiting researchers within those laboratories.

Position Summary
This position provides basic aquatic animal care and facility maintenance. The person in this position will care for aquatic animals by feeding, transferring animals to and from cages, maintaining clean cages, and applying medication as prescribed. The ability to follow posted instructions for all tasks related to the care of animals is critical in this position.

In order to provide a clean and safe environment in the lab, this position has the responsibility to perform general sanitation such as cleaning counters, sinks, walls, and floors with disinfectant. This work will involve the operation of mechanical cleaning equipment such as a cage washing machine and power sprayer. When needed, this position will assist with equipment maintenance and inventory.

Monitoring the health of the animals and record-keeping are important duties of this position. Animals are checked daily for findings of behavior, illness or injury and the information is recorded and reported as necessary. The ability to perform accurate identification and census counts of animals is another important aspect of this position.

This position will report to the Director of AqACS.

Work Conditions
Lab spaces are warm and humid at 83 degrees with 90 percent relative humidity. The position requires wearing protective equipment and involves direct contact with animals, repetitive tasks, and repetitive motions.

Work Schedule
Position works a flexible schedule and will be required to work weekends and holidays.

Minimum Requirements
• Six months of experience caring for animals (e.g., watering, feeding, bedding, housing, checking animals' health, etc.).

Professional Competencies
• Ability to follow detailed procedures and protocols.
• Ability to work independently.
• Ability to communicate effectively with individuals from diverse backgrounds and cultures.
• Computer literacy.

Preferred Qualifications
• Completed courses of professional development in aquatic animal husbandry, especially related to fish; 
OR
• An equivalent combination of training and experience in aquatic animal husbandry.

Link to Apply
http://careers.uoregon.edu/cw/en-us/job/523776/lab-animal-tech-1


Research Scientist/Engineer Assistant

Job Description

The University of Washington, Department of Pathology is a dynamic department that strives for a consistent level of high achievement in all of its activities. The Department offers full diagnostic services in all areas of Pathology, is a top ranked research organization as measured by research awards from the National Institutes of Health and offers an array of specialized educational training programs.

UW Medicine Pathology brings together state-of-the-art technology and highly trained, world renowned personnel to provide comprehensive diagnostic and personalized service to physicians, community hospitals, independent laboratories, and other health care organizations. Our operations are based at the University of Washington Medical Center, Harborview Medical Center, South Lake Union, Northwest Hospital and the Seattle Cancer Care Alliance. Pathology faculty members also serve at Seattle Children's Hospital, the Veteran’s Administration Puget Sound Healthcare System, and the Fred Hutchinson Cancer Research Center. These collaborative efforts have generated innovative, translational studies in the basic mechanisms of disease as they apply to diagnostic pathology.

The Chen lab in the Department of Pathology is seeking a fulltime Research Scientist/Engineer 2. The Chen lab integrates gene editing technology, functional genomics and cell-based and animal models to study pathogenesis of rhabdomyosarcoma, a rare and devastating pediatric cancer.

Laboratory Operations:
- Laboratory managerial duties such as ordering and stocking supplies and maintaining an orderly, safe and clean laboratory environment to ensure compliance with environmental health and safety guidelines and regulations.

- Attending lab meetings and presenting reports.

Data:
- Maintaining accurate and logical records of scientific data.
- Assisting in data analyses and manuscript preparation.

Animal work:

- Becoming proficient in writing, maintaining and submitting IACUC protocols.

- Tumor cell injections to establish tumor xenografts in immunocompromised mice and per diem management of mice.

- Microinjections of zebrafish, breeding and maintaining zebrafish lines.

Research Support:
- Independently performing or assisting with experiments related to cancer biology using techniques in molecular biology, cell-based assays, protein work, cell culture and animal work.

- Assisting in training new personnel.


Minimum Qualifications:
- Bachelor’s degree in biology, biochemistry or related fields

- Two years or more research experience (background in cancer research and/or animal models preferred but not required)
- Ability to work flexible hours based on experiment needs

Desired Qualifications:

- Strong organization and teaching skills

- Great team player, willing to work with others

- Ability to work efficiently and independently

- Excellent writing skills

- Command of Microsoft Word, Excel and PowerPoint programs

- Motivated to learn and enthusiastic about research

 If interested, please contact through e-mail the Principle Investigator of the laboratory, Eleanor Chen, and send along a CV and a list of 3 references.


PhD Project - University of Sheffield and Institute of Molecular and Cell Biology, Singapore

Can the nose taste?  Characterisation of a new cell type in the vertebrate olfactory system

Supervisors: Professor Tanya Whitfield, Associate Professor Suresh Jesuthasan

Application deadline: 30th April 2019

Project description:  Animals can sense diverse sensory stimuli, such as sound, light and smell.  This is usually mediated by distinct sense organs, such as the ears, eyes and nose.  Recently, it has become clear that some sensory cells can detect more than one sensory modality.  This project aims to study a distinctive cell type in the olfactory epithelium (nose) of zebrafish, with a shape characteristic of cells that sense mechanical or chemical cues, but which does not fit any known class of olfactory sensory neurons.  The successful applicant will use a combination of approaches to determine the functions of this new cell type: firstly, genes expressed by the cells will be characterised; secondly, neuronal connectivity will be defined, and thirdly, the student will attempt to disrupt development of this new cell type through genome editing.  By identifying specific genes expressed, the student will be able to identify which stimuli the cell is likely to detect, and will test their hypotheses using physiology and genetics.  The project will involve high-resolution image analysis and the use of transgenic animals or dye injection to determine anatomical connection to higher brain centres.  The project is expected to shape our understanding of how multi-sensory integration can influence animal behaviour.

We are seeking an enthusiastic student who is keen to embrace a range of experimental approaches to tackle a problem of sensory neuroscience.  The project offers the exciting opportunity of a two-year placement at a research institute in Singapore.

Key subject areas: Cell Biology / Development, Imaging, Genetics, Sensory Neuroscience


Funding:  This project is fully funded by a 4-year A*STAR Research Attachment Programme (ARAP) studentship.  This includes fees, stipend, travel, a settling-in allowance in Singapore, and research expenses.  Residency restrictions: awards are open to UK/EU citizens only.  Applicants should have, or expect to achieve, a First Class or 2.1 UK honours degree or equivalent in a relevant subject.

For informal enquiries about this project, please contact:

Professor Tanya Whitfield: Email: t.whitfield@sheffield.ac.uk
http://www.shef.ac.uk/bms/research/whitfield

Associate Professor Suresh Jesuthasan: Email: sureshjj@imcb.a-star.edu.sg
https://www.a-star.edu.sg/imcb/Science/Investigators/Joint-Adjunct-Pls-Profile/ResearchListID/94

Information about the A*STAR Research Attachment Programme can be found at:
https://www.a-star.edu.sg/language/en-SG/Scholarships/For-Graduate-Studies/A-STAR-Research-Attachment-Programme-ARAP

To apply, please fill in the University of Sheffield Postgraduate Online Application form:
https://www.sheffield.ac.uk/postgraduate/phd/apply/applying
https://www.sheffield.ac.uk/postgraduate/phd/apply


The USC Davis School of Gerontology is seeking a Research Lab Technician I to join its team!

This person will join a lab working on the molecular basis of aging and age-related diseases. This is an opportunity for a reliable and self-motivated person to participate in cutting-edge aging research. They will be working mainly with African turquoise killifish cells and tissues, and help manage our African fish colony. They will also assist with data generation and basic analysis derived from with aged turquoise killifish tissues, and will make contributions to projects in the laboratory. Primary responsibilities are to manage and genotype a colony of African turquoise killifish (including daily husbandry and feeding responsibilities). Other responsibilities include aspects of lab management support (i.e. ordering basic supplies, maintaining proper lab records).

Job responsibilities will include but are not limited to:
- Manage the husbandry of a small to medium fish colony (30-100 tanks).
- Perform basic experiments and data analysis to support lab members projects. Maintain detailed records of experiments, analyses and outcomes.
- Help train new lab members in fish husbandry techniques.
- Contribute to development of new research protocols and procedures or adaptation of existing protocols to the model.
- May contribute to publication of findings and present ongoing work and findings to colleagues at academic conferences. 
- Perform general lab maintenance as needed. Help maintain lab stocks, chemical inventory and safety records, and provide general lab support as needed. 

Our ideal candidate will have a Bachelor’s degree in biology or chemistry, or related field. They will be comfortable working with animals, in particular fish, and will have experience with PCR and western blotting. This position requires strong organizational skills, and the ability to interact with the PI and others lab members on a daily basis.

This position is funded by a research grant and may be funded by a subsequent grant. Accordingly, your position is contingent upon receipt of the necessary funding from this or any subsequent grant to continue employment. 

Benefits include a competitive salary, a rich array of USC benefits including healthcare (including dental and vision), 403(b), tuition reimbursement, national holidays, paid vacation and more. This is a full-time salaried position that will require substantial commitment and flexibility.

USC is an equal opportunity, affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other characteristic protected by law or USC policy. USC will consider for employment all qualified applicants with criminal histories in a manner consistent with the requirements of the Los Angeles Fair Chance Initiative for Hiring ordinance. 

If you are interested, please submit your application along with a cover letter and resume with references. 
Applications should be submitted through the USC career website:
https://usc.wd5.myworkdayjobs.com/ExternalUSCCareers/job/Los-Angeles-CA---University-Park-Campus/Research-Lab-Techinian-I_REQ20072763-1
Thank you for your interest!


We are seeking an outstanding postdoctoral candidate to join the Yeh Laboratory at Texas A&M University in College Station.  Our group uses interdisciplinary and quantitative approaches to study the molecular and cellular basis of embryonic development with specific focus on brain development.  In this context, we are interested in understanding how complex multi-enhancer regulatory landscapes interact with gene promoters through the application of super-resolution, live cell imaging.  A particular strength of the lab is the development of custom, state-of-the-art microscopy systems for applications in the life sciences. 

 

The candidate will be self-motivated, creative, and able to work collaboratively with a group of researchers with expertise in microscopy, physics, and developmental biology.  A PhD in the biological sciences (or related fields) with at least 3 years of laboratory research experience in zebrafish developmental biology is required.  Experience with quantitative imaging, in addition to experience in zebrafish development, will be considered positively, but is not required.  

 

This is a NIH-funded position with full benefits.  This position is renewable based upon good performance of the candidate and availability of funds.  Salary will be competitive and dependent on the level of experience of the candidate.  This position is currently open, and applications will be accepted until position is filled.

 

Applicants should provide,

·         cover letter describing research interests and career goals,

·         CV,

·         name and contact information from at least two references.

 

Applications should be submitted to Alvin Yeh, ayeh@tamu.edu