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In Vivo Analysis of Dynamic Cell Behaviors and Cell-Cell Interactions Underlying Blood Vessel Formation


We are inviting applications for a:

PhD position in Molecular Mechanisms of Vascular Morphogenesis at the Biozentrum, University of Basel


A PhD position is open in the Focal Area Growth and Development in the research group of Prof. Markus Affolter.


We offer an exciting international research environment at the Biozentrum in Basel to study the morphogenetic mechanisms of blood vessel formation in vivo. By using novel genetic approaches combined with high-resolution confocal live-imaging we are investigating the mechanisms of junctional remodeling during sprouting angiogenesis in the zebrafish embryo. The PhD project will involve the generation of tissue specific and inducible knock-out models in zebrafish and state-of-the-art in vivo imaging approaches to dissect protein dynamics during endothelial cell movements and cell-cell interactions. 


We are looking for highly motivated candidates with a solid background in genetics, molecular biology and cell biology.  Experience working with zebrafish is desired but not mandatory. Fluency in spoken and written English is required.


For further information, please refer to the following publications:

https://www.cell.com/cell-reports/fulltext/S2211-1247(14)00803-1

https://www.biorxiv.org/content/early/2017/11/01/212522

or consult the web pages of Prof. Markus Affolter 

(https://www.biozentrum.unibas.ch/research/groups-platforms/overview/unit/affolter/


Starting date by arrangement. Salary according to institutional guidelines. Please send a CV, a brief description of previous research experience and the names of three refer-ences to Dr. Heinz-Georg Belting (heinz-georg.belting@unibas.ch).

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