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A PhD student position is available in the laboratory of Prof. Matthias Hammerschmidt at the Biocenter of the University of Cologne, Germany, to contribute to our ongoing research on bone development and homeostasis in the zebrafish. The project will focus on the vertebral column. One part will deal with the roles of different growth factors (retinoic acid, BMP, FGF, Wnt etc.) and their interconnection during spine development at larval stages, the other with mutants isolated during our in-house forward genetics displaying scoliosis in juvenile and adult fish / post metamorphosis. The causative recessive mutation of one of the scoliosis mutants has been resolved, requiring confirmation via CRISPR/Cas genetics, as well as further in-depth phenotypic analyses, including state of the art imaging technologies including multiphoton confocal microscopy and microCT.

For further information, please visit our website (http://www.ag-hammerschmidt.zoologie.unikoeln.de/3.html) or contact us directly via email or telephone (see below).

The Cologne Biocenter is located in the center of Cologne, a very international and lively city, and offers an excellent scientific environment for the conducted research. The University of Cologne has been awarded the status of a “University of Excellence”, with our research group as part of the funded Cluster of Excellence CECAD. In addition, we are part of the Center for Molecular Medicine Cologne (CMMC).

 

Previous experience with the zebrafish is preferred, but not essential. Proficiency in English is required. To apply, please email your detailed CV and names of at least two referees to:

 

Hans-Martin Pogoda (senior scientist and Co-PI in Hammerschmidt lab)

pogodah@uni-koeln.de; phone: ++49-221-470 2738

Cologne University, Biocenter - Room 3-502, Zuelpicher Strasse 47b,

D-50674 Koeln, Germany

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