Postdoctoral Position-Vascular Development and Disease-University of Pittsburgh
Postdoctoral Position-Vascular Development and Disease-University of Pittsburgh
An NIH R01-funded postdoctoral position is available immediately in the laboratory of Dr. Beth Roman in the Department of Human Genetics at the University of Pittsburgh. We study the interplay between molecular and biomechanical pathways in the control of endothelial cell behavior and vascular development and disease. Our primary focus is on endothelial bone morphogenetic protein (BMP)/ALK1 signaling, which is disrupted in the genetic vascular disorder, hereditary hemorrhagic telangiectasia (HHT). We are looking for someone to lead studies exploring the molecular, cellular, and biomechanical basis for BMP ligand requirements in HHT, using zebrafish and primary endothelial cell culture models.
The University of Pittsburgh is a collaborative, collegial environment for biomedical research. Our laboratory is part of a large, interactive zebrafish community, and we are affiliated with the Heart, Lung, and Blood Vascular Medicine Institute (VMI), which houses numerous laboratories focused on clinical and basic cardiovascular research. The VMI offers numerous opportunities for collaboration and provides access to competitive T32 postdoctoral positions. We also collaborate with experts in biomechanics and structural biology, allowing cross-training in multiple disciplines.
Qualified candidates must have a PhD in a relevant field, a strong publication record, and excellent oral and written English communication skills. Expertise in molecular biology and experience with cell culture models is required. Previous experience with dynamic live-cell imaging, confocal microscopy, and zebrafish is preferred. Interested candidates should send a brief cover letter (maximum 1-page) summarizing scientific accomplishments and outlining motivation for this position; a full CV; and full contact information for three professional references to Dr. Beth Roman at romanb@pitt.edu.
For more information, please see
http://www.publichealth.pitt.edu/home/directory/beth-l-roman
http://www.upmc.com/Services/hht/Pages/default.aspx