Post-doc position available in the McCallion Lab - Johns Hopkins Univ. School of Medicine, Baltimore USA

My group employs cutting edge genomic and functional genetic approaches in mice, zebrafish and in vitro, integrating them with computational biology to connect sequence variation (coding and noncoding) with a better understanding of disease risk.   

The successful candidate will be expected to take a leading role in the implementation of studies to explore the genesis and application of chromatin catalogs and regulatory vocabularies for specific neuronal subtypes, and their application to understanding the impact of disease-associated variation. 

Functional evaluation of loci implicated in human cardiac conductance defects – GWAS/WES studies have now implicated a host of loci in sudden cardiac death (SCD) and various EKG traits. We have developed a genome editing and functional evaluation pipeline that includes EKG and ultrasound to study cardiac structure and function in zebrafish. 

The successful candidate will be expected to take a leading role in the implementation of studies to generate and analyze mutant models for selected candidate genes, determining their relevance to human disease. Candidates will be encouraged to seek independent fellowship funding but this is not a requirement for selection.  The PI has a strong track record of mentoring successful young scientists and is committed to career development and success of all his trainees. The successful applicant should be committed, curious and driven to achieve their full potential and seek the same for the people with whom they work. They should also possess a strong track record of publication.

To apply, please reach out to the PI by email (andy@jhmi.edu), submitting a c.v. (inc. list of references) and cover letter describing research experience and interests.