Research Associate - University of Massachusetts Medical School

A technician position is available in the Lawson Lab in the Department of Molecular, Cell and Cancer Biology (MCCB) at the University of Massachusetts Medical School.  This position will provide technical and logistical support for an active biomedical research laboratory that utilizes the zebrafish as a model system to study blood vessel development. 

Under the direction of the Principal Investigator or Designee, the Research Associate will plan, organize and perform work and experimental procedures referring major problems to them. The position will involve developing and evaluating new techniques and evaluating data, as well as assisting PI and others in carrying out experiments, maintaining lab organization, recordkeeping, artwork, keeping chemical waste records, ordering supplies and lab neatness.

The successful candidate will conduct research experiments and assist others in executing lab protocols and research experiments, primarily to do the following:

• Perform experiments on zebrafish embryos to study signals that regulate blood vessel development.
• Perform microinjections on early zebrafish embryos using mRNA, DNA or protein.
• Perform PCR-based genotyping on zebrafish embryos and adults. 
• Perform whole mount in situ hybridization and immuonstaining on fixed zebrafish embryos.
• Construct plasmids using common molecular biology techniques (e.g. restriction digest, gel purification, ligation, sequencing, etc.).

MAJOR RESPONSIBILITIES:

• Conducts in-depth analysis of research experiments
• Performs complex laboratory experiments
• Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
• Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
• May modify protocols and be responsible for a single, independent research project
• Assists in writing the text of scientific publications and grants.  Reviews literature
• Trains new laboratory personnel, students, and collaborators
• Maintains laboratory supplies and equipment
• Complies with all safety and infection control standards
• Perform other duties as required.

REQUIRED QUALIFICATIONS:  

• Bachelor’s degree in Biological Sciences, or equivalent experience
• 1 year relevant research experience
• Knowledge of Microsoft Office products
• Strong ability to analyze complex visual data in a quantitative and objective manner
• Judgment and action skills required to solve commonly encountered problems

Additional Information:

Knowledge of genetics, cell biology and molecular biology as well as proficient computer skills are strongly preferred.  Ability to interact with departmental and institutional offices is also beneficial. May train lower level technicians or students in the lab as necessary.

Physical Requirements may include manual dexterity to handle potentially hazardous chemicals and/or cleaners, visual acuity to perform duties safely in a scientific laboratory, and physical dexterity to lift 20-40 pound articles.

ENVIRONMENTAL WORKING CONDITIONS: 

Normal scientific laboratory conditions, may work with hazardous materials and unpleasant odors.

UMass Medical School is committed to being an equal opportunity and affirmative action employer and recognizes the power of a diverse community. We encourage applications from protected veterans, individuals with disabilities and those with varied experiences, perspectives and backgrounds to consider UMass Medical School as their employer of choice.