Postdoctoral Position - University of Alabama at Birmingham

A postdoctoral position is available this summer at the Department of Pharmacology and Toxicology at the University of Alabama at Birmingham. This position will focus on the phenotypic effects and their molecular basis due to the loss of sulfotransferase 4A1 function in zebrafish brain.  Participation in projects utilizing SULT4A1 manipulation in human cell culture and KO-mice.  SULT4A1 is an orphan sulfotransferase that is highly conserved in vertebrate evolution and is primarily expressed in neurons in the brain.  No enzymatic activity or molecular basis for its activity has been described.  Recent studies in our lab have indicated that deletion of the gene in zebrafish has a role in disrupting activity/sleep cycles in adult fish.  Projects will utilize multidisciplinary approaches including behavior, genetics, in vivo imaging, molecular and cell biology. We are looking for highly motivated, independent and creative individuals with good communication skills. Candidate must hold a recent doctorate in Basic Biomedical Sciences, Biology, Genetics, or related field. Previous experience with the zebrafish model, imaging, protein interactions, and bioinformatics is preferable.

 Interested applicants should send a cover letter detailing research experience and future interests, a Curriculum Vita, and contact details of three references to Dr. Charles Falany (cfalany@uab.edu).