Postdoctoral positions in Munich, Germany
The Sensory Biology & Organogenesis Research Unit at the Helmholtz Zentrum München is looking for candidates to take up postdoctoral positions (PhD positions may also be available for unusually talented students), for the following research lines:
1) Cellular mechanics during tissue development and repair, mainly applying a combination of high-end quantitative live imaging, optogenetics, cell biological approaches, genetics and computer modeling. This project is ideal for a biologist with a background in informatics, or a physicist or an engineer. The model system of choice is the zebrafish.
2) Cellular neurobiology, with an emphasis on sensorineural circuit mapping. The model systems are the zebrafish or Drosophila. Preference will be given to candidates with experience in optogenetics or electrophysiology.
3) Genetic and epigenetic regulation of neurogenesis. Preference will be given to candidates with a strong background or experience in molecular genetics and bioinformatics.
Candidates should be ambitious and independent. Recent doctorates (or about to obtain a PhD). At least one first-author publication in a high-profile journal is a must for postdoctoral candidates.
Applications should include a letter of presentation, a CV and the names and contact information of three academic references, and sent to:
Dr. Hernán López-Schier
Research Unit Sensory Biology & Organogenesis
Helmholtz Zentrum München
Ingolstädter Landstrasse 1
85764 Neuherberg - Munich,
Germanyhernan.lopez-schier@helmholtz-muenchen.de (mailto: hernan.lopez-schier@helmholtz-muenchen.de)
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Ingolstädter Landstr. 1
85764 Neuherberg
www.helmholtz-muenchen.de
Aufsichtsratsvorsitzende: MinDir´in Bärbel Brumme-Bothe
Geschäftsführer: Prof. Dr. Günther Wess und Dr. Nikolaus Blum
Registergericht: Amtsgericht München HRB 6466
USt-IdNr: DE 129521671
Postdoctoral position –University of Colorado School of Medicine.
An NIH funded Postdoctoral Fellow position to develop a zebrafish therapeutics screening model for remyelination studies in the central nervous system is available in the Department of Cell and Developmental Biology at the University of Colorado School of Medicine. This laboratory studies signaling pathways regulating oligodendrocyte development in the zebrafish and mouse CNS. More information about this laboratory is provided at our web site (http://www.ucdenver.edu/academics/colleges/medicalschool/departments/CellDevelopmentalBiology/facultyresearch/Pages/WendyMacklin.aspx).
A Ph.D. in neuroscience, molecular biology or genetics is required. The ideal candidate will have experience in zebrafish developmental genetics. Additional experience in transgenic/bac cloning methodologies and imaging would be particularly desirable, along with exposure to developmental neuroscience and/or glial biology. Interested applicants should submit a letter of interest with a curriculum vitae and arrange for three letters of recommendation to be sent to Wendy Macklin (wendy.macklin@ucdenver.edu).
Employer:
Yale University. New Haven, CT.
The Giraldez Lab, works on zebrafish and microRNAs.
http://www.yale.edu/giraldezlab
Job Description
Provide research assistance for a zebrafish genetics lab and aid with the maintenance of a freshwater tropical fish (zebrafish) facility under the supervision of the principal investigator of the laboratory. The focus of the overall project is to use zebrafish as a model system to study vertebrate development
Essential Duties of the Position
Feed fish, check and maintain water quality.
Breed fish and raise young.
Maintain tank and equipment.
Make up solutions, prepare fish food; limited laboratory maintenance.
Preferred: Experience in areas of molecular biology such as DNA cloning, PCR, tissue culture and microinjection.
Education and Training
Required: Bachelor’s degree in marine Biology, related field of Biology/Molecular biology, or two years of experience working in marine laboratories or molecular biology laboratories.
Skills and Abilities
Hands on experience in molecular biology; strong instrumentation skills.
High degree in independence, highly motivated, enthusiastic and strong work ethic.
Must be self-motivated and physically capable of maintaining 10-liter fish tanks in shelving units.
Requirements:
The applicant must be a US national or legal resident of the US.
Additional information http://www.yale.edu/giraldezlab
Where to send the applications:
Please send short description of your work experience including work with fish and molecular biology, contact information, CV and references in a single word or pdf document, including "zebrafish technician 2012" in the subject of the email
to: giraldezlab@gmail.com
Any application missing any of the above information will not be considered.
Review of the applications will begin on may 20th and will continue until a suitable candidate is identified
PhD POSITION
A position for a PhD student is available in the laboratory of Dr Martin Lowe to study the function of the inositol 5-phosphatase OCRL1 in endocytic membrane traffic. Loss of OCRL1 causes the human disorders Lowe syndrome and Dent-2, which are characterized by defects in the proximal renal tubules. This project will investigate the role of OCRL1 in endocytic trafficking in the kidney, and how its loss leads to the renal symptoms of these disorders. This work will be performed in zebrafish embryos, which we have recently used to model Lowe syndrome (Ramirez et al, Hum Mol Gen, 2012), using a variety of established methods. Information gained from these experiments will be used to generate a transgenic zebrafish reporter to screen for drugs to treat both Lowe syndrome and Dent disease.
This position, which is supported by the Lowe Syndrome Trust, is available from September 2012 and is supported by a stipend of £15,500 per annum. The deadline for applications is 30th May, 2012.
For further information and how to apply please go to: http://www.ls.manchester.ac.uk/phdprogrammes/results/studentships/projects/?id=855
Informal enquiries may be addressed to Martin Lowe at martin.lowe@manchester.ac.uk (tel: 0161 275 5387).
Zebra Danio Facility Manager – King’s College London
Biological Services
School of Biomedical Sciences
At King’s College London we are committed to the highest standards of care and welfare for animals used in medical research. A vacancy has arisen for an experienced zebra danio technologist to manage the new Zebra Danio Fish Facility, utilising the very latest technological innovations.
The successful candidate will lead the commissioning of the new zebrafish facility installation, comprising over 3700 tanks, and deliver the required services to research departments, while engendering a culture of care within the three zebrafish facilities.
You will be responsible for the managing a small technical team to care for zebra danios, working alongside skilled professionals committed to finding new cures for major diseases. Excellent communication skills will be required and you will be expected to develop and maintain a team ethos servicing the three zebra danio facilities.
An in depth knowledge of fish biosecurity, operation of barriers within a zebrafish facility, is an essential requirement of the post, along with the ability to organise and run complex breeding programmes.
The appointment will be made, dependent on relevant qualifications, within the Grade 6 scale, currently £31,020 to £37,012 per annum plus £2,323 per annum London Allowance.
Further details and application packs are available on the College’s website at www.kcl.ac.uk/jobs. All correspondence should clearly state the job title and reference number G6/QBC/321/12-MC. If you have any queries please contact your Recruitment Co-ordinator at hsrecruit6@kcl.ac.uk
The closing date for receipt of applications is 31st May 2012. Interviews will be held during June 2012.
Equality of opportunity is College policy.
Research Position-National Institutes of Health, Bethesda, MD
A Research Position to develop models for human diseases in zebrafish is available in the Cell Biology and Physiology Center (Rosa Puertollano, PI), at the National Institutes of Health (NIH). The successful candidate would join a multi-disciplinary and highly interactive team of researchers with diverse backgrounds and expertise in a collaborative scientific environment. We are interested in understanding the mechanisms that regulate traffic of lipids and proteins in the secretory and endocytic pathways, and how defects in sorting lead to human diseases. We use a wide range of cell biology techniques (molecular biology, protein biochemistry, confocal microscopy). Recently, we have started to translate our findings into in vivo animal models (mice and zebrafish). Our work on zebrafish includes in situ hybridization and immunohistochemistry of embryos, injection of RNA/DNA into embryos, production of transgenic lines, and use of zinc-finger nucleases for knock out generation.
Requirements:
We are seeking highly motivated, independent, creative and enthusiastic individuals. Candidate should have a Ph.D. and/or M.D. degree in cell biology, molecular biology, developmental biology or a closely related field. Prior experience in working with the zebrafish system, cell biology tools, and molecular genetics is essential. Salary is commensurate with research experience and accomplishments.
To Apply:
Applicants should send their curriculum vitae, a brief statement of research interests, and the names and contact information of three references to:
Rosa Puertollano Ph.D.
Investigator-Laboratory of Cell Biology
Building 50, Room 3537
50 South Drive, Bethesda, MD 20892-1454, USA
Email: puertolr@mail.nih.gov
DHHS/NIH IS AN EQUAL OPPORTUNITY EMPLOYER
The NIH is dedicated to building a diverse community in its training and employment programs.
A joint postdoctoral position is available in the laboratories of Dr. Arun Gosain and Dr. Jacek Topczewski at the Northwestern University Feinberg School of Medicine and Children’s Memorial Research Center, Chicago, Illinois. The successful candidate will be involved in study of the cranial bone and suture development in zebrafish in the team of researchers interested in basic and clinical aspects of skull development. Creative and strongly motivated candidates with experience using zebrafish models and/or skeletal biology are encouraged to apply. Please send a cover letter, previous research accomplishments, CV and a list of three individuals as references to j-topczewski@northwestern.edu
Postdoctoral Fellow Opportunity
Developmental Vascular Biology
Medical College Of Wisconsin, DEPARTMENT OF PEDIATRICS
POSITION PURPOSE
To independently perform studies that advance the goals of the principal investigator’s research projects in identifying targets for vascular related diseases.
ESSENTIAL DUTIES
Design and execute complex research procedures associated with small molecule discovery. Identify targets for drug discovery and develop, perform routine and complex protocols to identify small molecules that bind to these targets in an agonist or antagonist manner. Coordinate research study activities; lead and manage projects that relates to Dusp-5/small molecule project. Assist in developing patent applications for the small molecule or collection of molecules that targets Dusp-5. Participate in meetings with PI as it relates to leading the small molecule through the patenting process and final licensing. Participates in monthly meetings with computational biologists, organic chemists and synthetic chemists to help generate analogs for Dusp-5. Collaborate with principle investigators in determining study design and performing statistical analyses on all the results generated on small molecule targeting Dusp-5. Perform and develop routine and complex computational and database methods for identifying proteins that might participate in Dusp-5 signaling network in endothelial cells.
Develop new methodologies for projects related to drug discovery such as high throughput assays to assess analogs of small molecules that target Dusp-5. Maintain supplies, may negotiate with vendors, and track purchase orders as it relates to the project. Participate in Developmental Vascular Biology meetings with principle investigator and research staff and evaluate/interpret the validity of data.
May oversee the work of laboratory personnel including training and development as well as daily work direction/delegation/prioritizing. Assist in training of students, residents and fellows.
QUALIFICATIONS
PhD in a scientific field. Knowledge of scientific approach and methodologies with respect to zebrafish developmental biology. Interest in translating basic science discoveries to clinic. Ability to develop and follow research methodology and protocol. Knowledge of current technological developments/trends including hands-on experience with standard molecular biology and tissue culture techniques. Ability to read, understand, follow and enforce safety procedures. Ability to design, organize, and coordinates scientific research projects.
HOW TO APPLY:
Please visit the Medical College of Wisconsin’s Career Website: www.mcw.edu and apply for requisition #20000909 (Position #350.27020)
A postdoctoral position is available in the Bai lab at UT Southwestern Medical Center in Dallas. We use zebrafish as a genetic and developmental model in combination with the mammalian system to study transcriptional mechanisms that regulate the differentiation of hematopoietic stem cells (HSC). The potential project for this position will focus on identification of novel chromatin factors regulating HSC cell fate determination during normal and malignant hematopoiesis using a combination of genetic, biochemical and genomic approaches. The Bai lab is well funded to conduct cutting-edge researches and is part of the newly renovated Green Center forReproductive Biology Sciences, which is equipped with its own high-throughput genome sequencing center with strong bioinformatics support.
Self-motivated candidates with a Ph.D and/or M.D. in Biology related fields are encouraged to apply for the position. Experience with zebrafish and/or hematopoiesis-related research is helpful but not required. Salary will follow NIH guidelines commensuratewith training and experience.
If interested, please send your CV, names and contact information of three references, and a cover letter summarizing your research interests and future career aspirations (one pagelimit) to:
Xiaoying Bai, Ph.D
Assistant Professor
CPRIT Scholar in Cancer Research
Cecil H. and Ida Green Center for Reproductive Biology Sciences
The University of Texas Southwestern Medical Center at Dallas
Email: xiaoying.bai@utsouthwestern.edu
We are looking to recruit a scientist/manager to oversee the operations of our 3,000-tank zebrafish facility (completion date: October 2012). The candidate will support the scientific research of the newly founded Department Genes – Circuits – Behavior at the MPIN.
The job tasks include:
– Management of several hundred fish stocks,
– Supervision of animal care staff,
– Organization of collaborative screens,
– Shipping of zebrafish lines to outside laboratories,
– Training of new users,
– Compliance with government regulations (animal care, animal experiments, and S1).
Prior experience in zebrafish husbandry and genetics, very good knowledge of German and English and outstanding communication skills are required. This TVÖD position is paid according to experience and qualification and can be made permanent after a trial period.
An official advertisement will be posted on the institute's website. Please send informal inquiries to Ms. Annegret Cerny (cerny@neuro.mpg.de).
Dr. Herwig Baier
Max Planck Institute of Neurobiology
Am Klopferspitz 18
82152 München-Martinsried
Germany